![]() Constantine Blu- ray. Should you sell your soul to acquire a copy of 'Constantine' on Blu- ray? Reviewed by Martin Liebman, October 2. I guess God has a plan for all of us.
The Story Behind Alias' Infamous Red Wig and What Would Need to Happen for a Reboot. Alias, the spy- fi show that also included an old Italian prophet for some reason, put star Jennifer Garner in a number of wigs. But the bright red one she wore in the premiere still made the biggest impact. At the ATX Festival, the writers of Alias reunited, gave the usual vague answer about a reboot—“It would be amazing to do it; we’ve even talked with J. J. We wouldn’t want to do it unless it was absolutely perfect.”—and told stories of the show’s past. The best one, told by producer Sarah Caplan, was about the red wig sported by Sydney Bristow (Garner) in her rogue undercover mission in the premiere. After seeing three wigs that were the wrong shade of red, Caplan and J. J. Abrams saw a girl with hair that was blonde on top but the perfect shade of red at the tips. That’s when it got weird. Here’s what happened next, according to Caplain (via EW): I go to the girl, “Would you mind, can I take a little snippet of the bottom of your hair? We’re looking for this certain color. The director thinks yours is the perfect color.” She looks at me and she goes, “No.” I said, “Really? Why not?” “Well, I’ve grown this hair and that hair has been with me for 1. I only want a few hairs. Well, we’ll pay you for the little bit of hair.” By now she’s sitting down with her friends. She’s very smart. Finally, she agrees that we can buy a little bit of the hair. I don’t have any money on me, J. War Without End: A Brief History of the Muslim Conquests We tend to take the current military, economic, and technological superiority of the West relative to the. HISTORY OF ASPARTAME Modified and Additional Material by Arthur M. Evangelista, a former FDA Investigator Original Authors of the Two Main Components: Alex. HISTORY OF ASPARTAME. Modified and Additional Material by Arthur M. Evangelista, a former FDA Investigator. Original Authors of the Two Main Components: Alex Constantine and Gregory Gordon. Web Site: http: //www. Posted: 1. 2 March 2. The development of new pharmaceuticals was the focus of research at the international pharmaceutical company, G. D. Searle and Company (Farber 1. A group working on an ulcer drug was formed including Dr. Robert Mazer, James Schlatter, Arthur Goldkemp and Imperial Chemical. In particular, they were looking for an inhibitor of the gastrointestinal secretory hormone gastrin (Stegink 1. In 1. 96. 5, while creating a bioassay, an intermediate chemical was synthesized - - aspartylphenylalanine- methyl- ester (aspartame). In December of 1. James Schlatter was recrystalling aspartame from ethanol, the mixture spilled onto the outside of the flask. Some of the powder got onto his fingers. Later, when he licked his fingers to pick up a piece of paper, he noticed a very strong sweet taste. He realized that the sweet taste might have been the aspartame. So, believing that the dipeptide aspartame was not likely to be toxic, he tasted a little bit and discovered its sweet taste (Stegink 1. The discovery was reported in 1. Furia 1. 97. 2). 1. The investigators first reported the discovery of the artificial sweetener in the Journal of the American Chemical Society stating (Mazur 1. Preliminary tasting showed this compound to have a potency of 1. Nutra. Sweet, Spoonful, Equal.. These components are methanol, aspartic acid and phenylalanine (the latter being free form amino acids). It is used for making formaldehyde, acetic acid, methyl t- butyl ether (a gasoline additive), paint strippers, carburetor cleaners for your car's engine, and chloromethanes, et al. This poison can be inhaled from vapors, absorbed through the skin, and ingested. In aspartame, methanol poisoning and poisoning from methanol's breakdown components (formaldehyde and formic acid) can have widespread and devastating effects. This occurs in even small amounts, and is especially damaging when introduced with toxic, free- form amino acids, called excitotoxins. The methanol is converted into formaldehyde (a known carcinogen). Then, via aldehyde hydrogenase, the formaldehyde is converted to formic acid. These two metabolites of methanol are toxic and cumulative. Well, amino acids are good for us, right? Don't they keep us healthy? The answer is yes, amino acids are necessary for good health, EXCEPT when you separate the individual amino acid from its protein chain, and use it as an . An excitotoxin, is a deleterious substance that excites or over- stimulates nerve cells. This occurs in the brain, as well as the peripheral nerves, because aspartic acid, in free form, is an absorption accelerant & easily crosses the blood- brain barrier. Basically, they are a group of compounds that can cause special neurons within the nervous system to become overexcited to the point that these cells will die. Excitotoxins include such things as monosodium glutamate (MSG), aspartate, (a main ingredient in Nutra. Sweet), L- cysteine (found in hydrolyzed vegetable protein) and related compounds. It appears that an imbalance of these excitotoxins during critical periods of brain development can result in an abnormal formation of brain pathways; that is, a . Some neuroscienttists have voiced concern that America's explosion of childhood obesity may be related to excitotoxins in food. Information collected reveals that aspartame clinically exacerbates any borderline (even yet undetected) predisposing illness, and absolutely complicates certain known medical illnesses like Lupus, Multiple Sclerosis, Parkinson's, diabetes, retinopathies, allergies, mentation disorders, etc. This in NOT an allergic reaction, but rather a true toxin. No other food can be provided as a comparison to the toxic nature of Nutra. Sweet. Upon closer examination, the available research revealed that the manufacturer (Monsanto) and the FDA are manipulating the public (via the media) into thinking that aspartame is safe. As an American who trusted the system we all created, as an American who worked for the system, it made me angry that public health has taken a backseat to greed. This is the . Searle approached Dr. Harry Waisman, Biochemist, Professor of Pediatrics, Director of the University of Wisconsin's Joseph P. Memorial Laboratory of Mental Retardation Research and a respected expert in phenylalanine toxicity, to conduct a study of the effects of aspartame on primates. The study was initiated on January 1. April 2. 5, 1. 97. Waisman died unexpectedly in March, 1. One died after 3. Five others (out of seven total) had grad mal seizures. The actual results were hidden from the FDA when G. D. Searle submitted its initial applications. Searle denied knowledge of or involvement with the initiation, design or performance of the study. Yet, false results were submitted to the FDA like the rest of the 1. G. D. Searle studies (on aspartame and other products), bearing a Searle Pathology- Toxicology project number. Waisman and G. D. Searle were responsible for the study design. A number of false statements were made by G. D. Searle including that the animals were unavailable for purchase for autopsy after the termination of the study. Robert Scheuplein, who was the acting Director of FDA's Toxicological Services Center for Food Safety and Applied Nutrition was quoted as saying . Olney found that oral intake of glutamate, aspartate and cysteine, all excitotoxic amino acids, cause brain damage in mice (Olney 1. Olney informed G. D. Searle that aspartic acid caused holes in the brains of mice. Searle and who has done research for the Glutamate (MSG) Association, and was asked to confirm Dr. Olney's tests. Reynolds confirmed aspartame's neurotoxicity in infant mice. The reason for the latter is likely the fact that the blood brain barrier closes most slowly (if ever completely) around structures like hypothalamus. The outcome for such animals (rats) was obesity,severe behavioral changes, etc. Searle did not inform the FDA of this study until after aspartame's approval. None of the tests submitted by G. D. Searle to the FDA contradicted these findings (Olney 1. Gordon 1. 98. 7, page 4. US Senate 1. 98. 7). Searle memo laid out the strategy for getting aspartame approved (Helling 1. At this meeting . It would help if we can get them or get their people involved to do us any such favors. This would also help bring them into subconscious spirit of participation.(Refer to Actual Letter.. FDA Toxicologist Dr. Adrian Gross came upon some irregularities in the submitted tests of the G. D. Searle drug Flagyl. Searle did not respond for another two years. Their response raised serious questions about the validity of their tests (Gross 1. On March 5, 1. 97. G. D. Searle's petition to the FDA for approval to market aspartame as a sweetening agent was published in the Federal Register (1. Background: In August of 1. G. D. Searle conducted two 7. Aldactone. One study was conducted at G. D. Searle and one at Hazelton Laboratories. For confirmation of the results, G. D. Searle sent the slides to Biological Research, Ltd. Jacqueline Mauro examined the data. She discovered that the drug appeared to induce tumors in the liver, testes, and thyroid of the rats. The report submitted to G. D. Searle by Dr. Mauro was known as the MBR Report. Searle's Mathematics- Statistics Department. Searle contracted with another pathologist, Dr. The Willigan Report was more to G. D. Searle's liking because it revealed a statistically significant increase in thyroid and testes tumors, but not in liver tumors. Liver tumors are of much more concern to the FDA. The Willigan Report was immediately submitted to the FDA. Searle did not disclose the MBR Report to the FDA until August 1. G. D. Searle claimed that they did not submit the MBR Report to the FDA because of an . The idea that two naturally- occurring amino acids could harm someone in relatively small amounts... Freeman, M. D. Searle in their petition to approve aspartame (Freeman 1. Freeman pointed out the inadequacy of single- dose tests of aspartame as early as 1. That's what they did with Nutra. Sweet. Results are reported in narrative summary form, and tabulations of mean average values only. Freeman concludes. The administration of Aspartame, as reported in these studies at high dosage levels for prolonged periods, constitutes clinical investigational use of a new drug substance. The information submitted for our review is inadequate to permit a scientific evaluation of clinical safety. The FDA Bureau of Foods rejected Dr. Freeman's recommendation.(Congressional Record 1. Construction of a large aspartame manufacturing plant in Augusta, Georgia was halted. It was thought that aspartame's uncertain regulatory future was the main reason for the stopping of construction (Farber 1. In the 1. 97. 3 G. D. Searle Annual Report, an executive stated that . Searle to the FDA were conducted in the early to mid- 1. All of the tests that were described by the FDA as . Eighty percent of these tests were conducted by G. D. Searle or by their major contractor, Hazleton Laboratories, Inc.(Graves 1. S5. 49. 7 of Congressional Record 1. Richard Crout, the acting director of the FDA Bureau of Drugs stated that . No protocols, manufacturing controls information or preclinical data were provided. John Olney and Consumer Interest attorney, James Turner, Esq. Searle to discuss the results of Olney's experiments. Searle representative's claim that Olney's data raises no health concerns. He acted on a strong endorsement from the Bureau of Foods, now called the Center for Food Safety and Applied Nutrition (CFSAN). This approval came despite the fact that FDA scientists found serious deficiencies in all of the 1. G. D. John Olney, a Washington University neuropathologist who had linked aspartame to brain lesions in mice.
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